Matthew 25: Ministries began as the result of a trip Founder and President Rev. Wendell Mettey made with a group of doctors and nurses to Nicaragua in 1990. After seeing the seemingly endless poverty and devastation, Pastor Mettey made a promise to himself that he would find a way to help the people of Nicaragua and others in similar need. 

Upon returning, Pastor Mettey developed a system to recover excess products which were deemed no longer useful by U.S. corporations, and redistribute these items to people in desperate poverty.

Since 1991, Matthew 25: Ministries has grown from a small suitcase ministry to an international relief organization distributing 10 million pounds of products each year. In total, M25M has sent more than 125 million pounds of aid across the United States and into more than thirty-five countries worldwide.

In May, 2004, Matthew 25: Ministries purchased a 168,000 square foot facility, the Center for Humanitarian Relief. Since the purchase of this space, M25M has responded to 19 major disasters including cyclones, tsunamis, earthquakes, floods, hurricanes, windstorms, and droughts. In response to the 2010 earthquake in Haiti, Matthew 25: Ministries sent medical mission teams and shipped disaster relief products throughout the Port-au-Prince area.